Lewis C. Cantley
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چکیده
منابع مشابه
Lewis C. Cantley
Nations Development Programme), and now also involves several other international organisations. MFF focuses on the countries worst hit by the 2004 tsunami, i.e. India, Indonesia, Maldives, Seychelles, Sri Lanka, and Thailand. While highlighting mangroves as an important flagship ecosystem of its efforts in the region, the MFF is also looking at the conservation of other features, including cor...
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Lewis C. Cantley, Director of the Sandra and Edward Meyer Cancer Center at Weill Cornell Medicine, is a world leader in cancer and metabolic disease research. His seminal discoveries have shed light on the regulation of ion pumps and other transport proteins, insulin-mediated regulation of glucose metabolism and the role of signal transduction networks in cell transformation. At Tufts Universit...
متن کاملScales of Lewis basicities toward C-centered Lewis acids (carbocations).
Equilibria for the reactions of benzhydryl cations (Ar2CH(+)) with phosphines, tert-amines, pyridines, and related Lewis bases were determined photometrically in CH2Cl2 and CH3CN solution at 20 °C. The measured equilibrium constants can be expressed by the sum of two parameters, defined as the Lewis Acidity (LA) of the benzhydrylium ions and the Lewis basicity (LB) of the phosphines, pyridines,...
متن کاملGeminal phosphorus/aluminum-based frustrated lewis pairs: C−H versus C≡C activation and CO2 fixation.
Geminal phosphorus/aluminum-based frustrated Lewis pairs (FLPs) are easily obtained by hydroalumination of alkynylphosphines. These FLPs can activate terminal acetylenes by two competitive pathways, which were analyzed by DFT calculations, and they can bind carbon dioxide reversibly. Therefore, alongside polyfluorinated boranes, alanes are also ideal Lewis acids for FLP chemistry. NOTE: The wor...
متن کاملC-Type Lectins and Sialyl Lewis X Oligosaccharides
Carbohydrates are major components of the outer surface of mammalian cells and these carbohydrates are very often characteristic of cell-types and developmental stages (Feizi, 1985; Hakomori, 1985). One of such cell type–specific carbohydrates is sialyl Lewis X, NeuNAc a 2 → 3Gal b 1 → 4(Fuc a 1 → 3)GlcNAc → R. Sialyl Lewis X and Lewis X, Gal b 1 → 4(Fuc a 1 → 3)GlcNAc, were originally discover...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2009
ISSN: 0960-9822
DOI: 10.1016/j.cub.2009.06.010